GeneGene: SERPINA1

Alpha-1 antitrypsin (SERPINA1)

SERPINA1 encodes alpha-1 antitrypsin, the main inhibitor of neutrophil elastase in the lung. Deficiency leaves lung tissue unprotected from enzymatic destruction; augmentation aims to restore protective protein levels directly to the airways.

1
Drugs
1
Trials tracked
0
Resolved
1
Indications

Drugs hitting this target

Trials targeting AAT / SERPINA1

1 benchmark

Indications

About AAT / SERPINA1

What is AAT / SERPINA1?

SERPINA1 encodes alpha-1 antitrypsin, the main inhibitor of neutrophil elastase in the lung. Deficiency leaves lung tissue unprotected from enzymatic destruction; augmentation aims to restore protective protein levels directly to the airways.

Which drugs target AAT / SERPINA1?

Therapies acting on AAT / SERPINA1 tracked here include Inhaled alpha-1 antitrypsin.

References