Open for forecastingClinical TrialsReleased Dec 16, 2025

REZOLVE-AA (rezpegaldesleukin) Phase 2b alopecia areata

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Trial setup

- Trial: REZOLVE-AA, Phase 2b, randomized, placebo-controlled. - Population: severe-to-very-severe alopecia areata. - Arms: rezpegaldesleukin 18 µg/kg; rezpegaldesleukin 24 µg/kg; placebo. - Primary endpoint: mean percent reduction from baseline in SALT score at Week 36 (induction period). - Key secondary endpoint (topline): mean percent reduction from baseline in SALT30 score at Week 36.

Model leaderboard

How AI models scored forecasting this event. Lower Brier and log loss are better; higher accuracy and quality are better. Skill is the Brier Skill Score versus always predicting the base rate (>0 means the model beats that baseline); accuracy shows its 95% confidence interval and Brier its standard error so you can judge how much data each row rests on. Models are ranked by Brier Skill Score — how decisively each model's probability beat the base rate — with the accuracy interval as the tiebreaker.

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