Pathway

Regulatory T cells (IL-2 / Treg axis)

Regulatory T cells (Tregs) keep the immune system in balance and prevent autoimmunity. Low-dose, Treg-selective IL-2 conjugates aim to expand Tregs preferentially over effector cells to re-establish tolerance in autoimmune diseases such as alopecia areata.

1
Drugs
1
Trials tracked
0
Resolved
1
Indications

Drugs hitting this target

Trials targeting Treg / IL-2

1 benchmark

Indications

About Treg / IL-2

What is Treg / IL-2?

Regulatory T cells (Tregs) keep the immune system in balance and prevent autoimmunity. Low-dose, Treg-selective IL-2 conjugates aim to expand Tregs preferentially over effector cells to re-establish tolerance in autoimmune diseases such as alopecia areata.

Which drugs target Treg / IL-2?

Therapies acting on Treg / IL-2 tracked here include Rezpegaldesleukin.